Michael J. Schnieders

Michael J. Schnieders

Assistant Professor of Biomedical Engineering

Assistant Professor of Biochemistry

(319) 335-7891
5013 Seamans Center for the Engineering Arts and Sciences
Joined the College of Engineering: 
2012
Education: 
PhD, Biomedical Engineering, Washington University in St. Louis, 2007
BSE, Biomedical Engineering, University of Iowa, 1999
Special Fields of Knowledge: 
Molecular biophysics theory and high performance computational algorithms that are essential to reducing the time and cost of engineering new pharmaceuticals.
Present Research Interests: 
Next generation theory and tools for biomolecular x-ray crystallography; prediction of the structure, thermodynamics and solubility of drug tablets; personalized medicine: from genome sequencing to molecular phenotypes; biomolecular electrostatics and high-performance computing
Selected Publications: 
  • Schnieders, M. J., Kaoud, T. S., Yan, C., Dalby, K. N., and Ren, P. (2012) Computational insights for the discovery of non-ATP competitive inhibitors of MAP kinases, Current Pharmaceutical Design 18, 1173-1185.
  • Schnieders, M. J., Baltrusaitis, J., Shi, Y., Chattree, G., Zheng, L., Yang, W., and Ren, P. (2012) The Structure, Thermodynamics, and Solubility of Organic Crystals from Simulation with a Polarizable Force Field, Journal of Chemical Theory and Computation 8, 1721-1736.
  • Schnieders, M. J., Fenn, T. D., and Pande, V. S. (2011) Polarizable atomic multipole X-ray refinement: Particle mesh Ewald electrostatics for macromolecular crystals, Journal of Chemical Theory and Computation 7, 1141-1156.
  • Fenn, T. D., and Schnieders, M. J. (2011) Polarizable atomic multipole X-ray refinement: weighting schemes for macromolecular diffraction, Acta Crystallographica Section D 67, 957-965.
  • Ponder, J. W., Wu, C., Ren, P., Pande, V. S., Chodera, J. D., Schnieders, M. J., Haque, I., Mobley, D. L., Lambrecht, D. S., DiStasio, R. A., Head-Gordon, M., Clark, G. N. I., Johnson, M. E., and Head-Gordon, T. (2010) Current status of the AMOEBA polarizable force field, Journal of Physical Chemistry B 114, 2549-2564.
Active Scientific and Professional Society Memberships: 
Biophysical Society, American Chemical Society