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Kai Tan

kai-tan@uiowa.edu

Photo of Nicole GroslandAssistant Professor
Internal Medicine

Assistant Professor
Biomedical Engineering

Professor
Applied Mathematical and Computational Sciences

2294 Carver Biomedical Research Building
The University of Iowa
Iowa City, IA 52242
Telephone: (319) 384-4676

Personal Web Site

Joined the College of Engineering: 2008

Education: Ph.D., Biochemistry, Washington University, 2004.
B.A., Biochemistry, Beloit College, 1997

Special Fields of Knowledge: Systems biology, bioinformatics, comparative genomics, gene regulation.

Present Research Interests: understanding gene regulatory networks and molecular pathways that give rise to stem cell phenotype and human diseases.

Selected Publications:

  • Firpi HA, Ucar D, and Tan K. Discover regulatory DNA elements using chromatin signature and artificial neural network. 2010. Bioinformatics. 26 (13):1579-86.
  • Tan K, Tegner J, and Ravasi T. Integrated approaches to uncover transcriptional regulatory networks in mammalian cells.  Genomics. 91(3):  219-231, 2008.
  • Tan K, Feizi H, Luo C, Fan S, Ravasi T, and Ideker T.  A systems approach to delineate functions of paralogous transcription factors: Role of the Yap family in the DNA damage response.  Proc. Natl. Acad. Sci.  105(8):2934-2939, 2008.
  • Tan K, Shlomi T, Feizi H, Ideker T, and Sharan R.  Transcriptional regulation of protein complexes within and across species. Proc. Natl. Acad. Sci.  104(4):  1283-1288, 2007.
  • Tan K, Ideker T.  Protein interaction networks in Biological networks.  World Scientific, New Jersey.  2007.

Active Scientific and Professional Society Memberships: International Society for Computational Biology; International Society for Systems Biology; Sigma Xi, International Society for Stem Cell Research.

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