Kai Tan

Joined the College of Engineering: 2008

Education: Ph.D., Biochemistry, Washington University, 2004.
B.A., Biochemistry, Beloit College, 1997

Special Fields of Knowledge: Systems biology, bioinformatics, comparative genomics, gene regulation.

Present Research Interests: understanding gene regulatory networks and molecular pathways that give rise to stem cell phenotype and human diseases.

Selected Publications:

• Tan K, Tegner J, and Ravasi T. Integrated approaches to uncover transcriptional regulatory networks in mammalian cells.  Genomics. 91(3):  219-231, 2008.
• Tan K, Feizi H, Luo C, Fan S, Ravasi T, and Ideker T.  A systems approach to delineate functions of paralogous transcription factors: Role of the Yap family in the DNA damage response.  Proc. Natl. Acad. Sci.  105(8):2934-2939, 2008.
• Tan K, Shlomi T, Feizi H, Ideker T, and Sharan R.  Transcriptional regulation of protein complexes within and across species. Proc. Natl. Acad. Sci.  104(4):  1283-1288, 2007.
• Tan K, McCue LA, and Stormo GD.  Making connections between novel transcription factors and their DNA motifs. Genome Research. 15(2):  312-320, 2005.
• Tan K, Ideker T.  Protein interaction networks in Biological networks.  World Scientific, New Jersey.  2007.

Active Scientific and Professional Society Memberships: International Society for Computational Biology; International Society for Systems Biology; Sigma Xi, International Society for Stem Cell Research.