Roger Kamm to Present Grabbing the Globe Seminar March 28

Tuesday, March 26, 2013

Roger Kamm, Cecil and Ida Green Distinguished Professor of Biological Engineering and Mechanical Engineering at the Massachusetts Institute of Technology, will present “Microfluidics: A powerful tool to study multi-cell interactions in metastatic cancer,” at 3:30 p.m., March 28 in W151 Pappajohn Business Building.

The "Grabbing the Globe" Seminar Series is designed to prepare Engineering students for global success. It recognizes the late UI Distinguished Engineering Alumni Academy member and retired Exxon USA president and CEO Randall Meyer and his wife, Barbara.

Metastatic cancer often involves a sequence of events: the separation of individual cells from the primary tumor, migration through the host tissue under the action of biochemical gradients and physical factors such as interstitial flow, intravasation into the vascular system, extravasation at a remote site, and the colonization, growth and vascularization of a peripheral tumor.  Studies have been performed using various designs of a microfluidic platform to simulate several stages of metastasis.  Selected studies will be presented addressing several of these phenomena.

A primary objective of Kamm’s research has been the application of fundamental concepts in fluid and solid mechanics to better understand essential biological and physiological phenomena.  Spanning a wide range, research in the Kamm lab has addressed issues in the respiratory, ocular and cardiovascular systems. 

More recently, his attention has focused on two areas, the molecular mechanisms of cellular force transmission and sensing, and the development of new microfluidic technologies for cancer or vascularized engineered tissues. He is the 2010 recipient of the Lissner Award from the American Society of Mechanical Engineers and a member of the Institute of Medicine.  He is past chair of the US National Committee on Biomechanics and of the World Council on Biomechanics and is current Chair of the International Academy of Medical and Biological Engineering.  He currently directs a new NSF Science and Technology Center on Emergent Behaviors of Integrated Cellular Systems.