Wahle A, Sonka M:
In:
Studies in Health, Technology and Informatics, IOS Press, Amsterdam
Volume 113, Page 321-359, 2005
This comprehensive book chapter reiterates the details of the fusion methodology, in-vitro and in-vivo validation, summarizes the applications in intravascular brachytherapy and morphology/plaque as well as computational hemodynamics in human coronary arteries (Table of Contents) (Links)
Abstract: Imaging of the coronary arteries is usually performed by X-ray contrast angiography or intravascular ultrasound (IVUS). Angiography provides information about the vessel lumen and its geometry. IVUS offers more detailed information that also includes the vascular wall. The chapter describes these two imaging modalities and their geometrically correct fusion yielding a 3-D and/or 4-D representation of the coronary geometry and morphology. The image-derived information is used for assessment of coronary function and plaque severity, blood flow related indices are determined using computational fluid dynamics. Detailed description of the methodology is followed by validation and clinical studies.
Note: Figures 25-28 (pp. 346-349) contain color but were reproduced in grayscale only in the printed book; this addendum contains the respective figures in color (PDF file, 1801 KB).