Research in Cardiovascular fluid Biomechanics include blood vessel reactivity with development of atherosclerosis; computational fluid dynamic and finite element modeling of blood vessels reconstructed from intravascular ultrasound imaging with developing lesion in an animal model to relate fluid mechanical stresses and vascular material property alterations with lesion growth; fluid mechanics in coronary and carotid arteries with stenosis reconstructed from intravascular and angiographic imaging, mechanical valve closure dynamics and its relationship with thrombus formation and valve cavitation.
Research in cardiovascular solid biomechanics include biomechanical studies of abdominal aortic aneurysm and cerebral aneurysm to understand pathogenesis of these diseases and diagnose rupture risk; In vitro development of aneurysm using elastase treatment; Mechanical testing and constitutive modeling of biologic soft tissues; Biomechanics of endovascular surgery and vascular graft design; Finite element method, 3D surface smoothing, mesh refinement and analysis.
Associated Faculty: K.B. Chandran; M.L. Raghavan; Sarah C. Vigmostad
